Microscale flow dynamics of red blood cells in microchannels: An experimental and numerical analysis

R. Lima, M. Nakamura, T. Omori, T. Ishikawa, S. Wada, T. Yamaguchi

研究成果: Conference contribution

9 被引用数 (Scopus)

抄録

The blood flow dynamics in microcirculation depends strongly on the motion, deformation and interaction of red blood cells (RBCs) within the microvessel. We present confocal micro-PTV measurements on the motion of individual RBCs through a circular polydimethysiloxane (PDMS) microchannel. The RBC radial displacement and dispersion calculated from these measurements show that the RBC paths are strongly dependent on the both Hct and plasma layer. In order to obtain more detailed information of the non-Newtonian property of blood a novel computational scheme is also described. The simulated flow dynamics were in good agreement with the Casson flow model and in vivo observations. In the near future by comparing both results we hope to clarify a variety of complex phenomena occurring at the microscale level.

本文言語English
ホスト出版物のタイトルAdvances in Computational Vision and Medical Image Processing
ホスト出版物のサブタイトルMethods and Applications
編集者Joao Manuel, R.S. Tavares, R.M. Natal Jorge
出版社Springer
ページ203-220
ページ数18
ISBN(印刷版)9781402090851
DOI
出版ステータスPublished - 2009
イベント1st ECCOMAS Thematic Conference on Computational Vision and Medical Image processing, VIPimage 2007 - Porto, Portugal
継続期間: 2007 10 172007 10 19

出版物シリーズ

名前Computational Methods in Applied Sciences
13
ISSN(印刷版)1871-3033

Other

Other1st ECCOMAS Thematic Conference on Computational Vision and Medical Image processing, VIPimage 2007
国/地域Portugal
CityPorto
Period07/10/1707/10/19

ASJC Scopus subject areas

  • 土木構造工学
  • モデリングとシミュレーション
  • 生体医工学
  • コンピュータ サイエンスの応用
  • 流体および伝熱
  • 計算数学
  • 電子工学および電気工学

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