Micropatterned polymeric nanosheets for local delivery of an engineered epithelial monolayer

Toshinori Fujie, Yoshihiro Mori, Shuntaro Ito, Matsuhiko Nishizawa, Hojae Bae, Nobuhiro Nagai, Hideyuki Onami, Toshiaki Abe, Ali Khademhosseini, Hirokazu Kaji

研究成果: Article査読

41 被引用数 (Scopus)

抄録

Like a carpet for cells, micropatterned polymeric nanosheets are developed toward local cell delivery. The nanosheets direct morphogenesis of retinal pigment epithelial (RPE) cells and allow for the injection of an engineered RPE monolayer through syringe needles without the loss of cell viability. Such an ultrathin carrier has the promise of a minimally invasive delivery of cells into narrow tissue spaces.

本文言語English
ページ(範囲)1699-1705
ページ数7
ジャーナルAdvanced Materials
26
11
DOI
出版ステータスPublished - 2014 3 19

ASJC Scopus subject areas

  • 材料科学(全般)
  • 材料力学
  • 機械工学

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