Micro/nano-patterned surfaces for control of cell adhesion and cell functions: Differentiation into adipocytes

Makiko Goto, Kae Sato, Takehiko Tsukahara, Tomohiro Konno, Kazuhiko Ishihara, Takehiko Kitamori

研究成果: Paper査読

1 被引用数 (Scopus)

抄録

Cell adhesion surfaces having micro/nano patterns and controlled chemical properties were fabricated. The patterning at a subcellular-scale should control the formation of focal adhesion formation that plays an important role in many cellular functions. We observed that preadipocytes adhered, proliferated on the surfaces, and were induced to differentiate. Individual cells adhered and grew on the patterns but confluent cell monolayers on nano patterns easily detached from the substrata. The micro/nano patterns provide cells with unique scaffolds controlling cell-matrix interactions at a subcellular scale.

本文言語English
ページ993-995
ページ数3
出版ステータスPublished - 2006 1 1
外部発表はい
イベント10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 - Tokyo, Japan
継続期間: 2006 11 52006 11 9

Other

Other10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006
国/地域Japan
CityTokyo
Period06/11/506/11/9

ASJC Scopus subject areas

  • 化学工学(その他)
  • バイオエンジニアリング

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