Cell adhesion surfaces having micro/nano patterns and controlled chemical properties were fabricated. The patterning at a subcellular-scale should control the formation of focal adhesion formation that plays an important role in many cellular functions. We observed that preadipocytes adhered, proliferated on the surfaces, and were induced to differentiate. Individual cells adhered and grew on the patterns but confluent cell monolayers on nano patterns easily detached from the substrata. The micro/nano patterns provide cells with unique scaffolds controlling cell-matrix interactions at a subcellular scale.
|出版ステータス||Published - 2006 1 1|
|イベント||10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 - Tokyo, Japan|
継続期間: 2006 11 5 → 2006 11 9
|Other||10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006|
|Period||06/11/5 → 06/11/9|
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