Microchip-based rapid sample-preparation for gas-chromatography assay of amphetamine-type stimulants in urine specimens

Hajime Miyaguchi, Manabu Tokeshi, Yoshikuni Kikutani, Akihide Hibara, Hiroyuki Inoue, Takehiko Kitamori

研究成果: Paper査読

抄録

As the first application of pressure-driven microfluidics in forensic toxicology, a microchip-based liquid-liquid extraction for the gas-chromatography assay for amphetamine-type stimulants in urine has been developed. The interface consisting of 1-chlorobutane and alkalized urine was stabilized in the asymmetric microchannel modified partially with the capillarity restricted modification (CARM) method. As a practical demonstration, methoxyphenamine hydrochloride was administered to three healthy volunteers, and the concentration of methoxyphenamine in their urine was determined.

本文言語English
ページ936-938
ページ数3
出版ステータスPublished - 2006
外部発表はい
イベント10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 - Tokyo, Japan
継続期間: 2006 11 52006 11 9

Other

Other10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006
国/地域Japan
CityTokyo
Period06/11/506/11/9

ASJC Scopus subject areas

  • 化学工学(その他)
  • バイオエンジニアリング

フィンガープリント

「Microchip-based rapid sample-preparation for gas-chromatography assay of amphetamine-type stimulants in urine specimens」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル