As the first application of pressure-driven microfluidics in forensic toxicology, a microchip-based liquid-liquid extraction for the gas-chromatography assay for amphetamine-type stimulants in urine has been developed. The interface consisting of 1-chlorobutane and alkalized urine was stabilized in the asymmetric microchannel modified partially with the capillarity restricted modification (CARM) method. As a practical demonstration, methoxyphenamine hydrochloride was administered to three healthy volunteers, and the concentration of methoxyphenamine in their urine was determined.
|出版ステータス||Published - 2006|
|イベント||10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 - Tokyo, Japan|
継続期間: 2006 11 5 → 2006 11 9
|Other||10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006|
|Period||06/11/5 → 06/11/9|
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