Methylmercury binds to a low molecular weight substance in rabbit and human erythrocytes

Akira Naganuma, Nobumasa Imura

研究成果: Article査読

63 被引用数 (Scopus)

抄録

Behavior of methylmercury in animal blood was investigated by gel filtration of stroma-free hemolysates from rat, rabbit, and human erythrocytes, treated with methylmercury. In the rabbit and human erythrocytes, methylmercury was bound to a low molecular weight substance rather than hemoglobin, while almost all of methylmercury in the rat erythrocyte was bound to the hemoglobin fraction. The methylmercury-bound substance of low molecular weight in rabbit erythrocytes showed a similar behavior pattern to that of glutathione (GSH) bound with methylmercury on gel filtration with Sephadex G-15 and thin-layer chromatography.

本文言語English
ページ(範囲)613-616
ページ数4
ジャーナルToxicology and Applied Pharmacology
47
3
DOI
出版ステータスPublished - 1979 3 15

ASJC Scopus subject areas

  • 毒物学
  • 薬理学

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