Melanotic neuroectodermal tumor of the brain recurring 12 years after complete remission: Case report

Shunsuke Omodaka, Ryuta Saito, Toshihiro Kumabe, Jun Kawagishi, Hidefumi Jokura, Yukihiko Sonoda, Mika Watanabe, Takamasa Kayama, Teiji Tominaga

研究成果: Article査読

13 被引用数 (Scopus)

抄録

We describe a rare case of melanotic neuroectodermal tumor (MNT) of the brain recurring 12 years after complete remission. An 11-year-old girl initially presented with exotropia and bilateral papilledema. Magnetic resonance (MR) imaging revealed an intracranial extraaxial large tumor at the midfrontal region. T1-weighted MR imaging showed the tumor to be well delineated with homogeneous enhancement by gadolinium. The tumor was subtotally removed, and the histological diagnosis was MNT. The residual tumor became enlarged, so gamma knife radiosurgery was performed 5 months after initial surgery. The enhanced lesion disappeared, but another lesion emerged 3 years later. A second gamma knife radiosurgery was performed for this local recurrence. The enhanced lesion disappeared once again. Twelve years after the second gamma knife radiosurgery, another local recurrence was detected. This tumor was subtotally removed. Histological examination confi rmed the same diagnosis of MNT. This case suggests that MNTs not completely resected need long-term follow up, even if complete remission was achieved after adjuvant therapy.

本文言語English
ページ(範囲)51-57
ページ数7
ジャーナルBrain Tumor Pathology
27
1
DOI
出版ステータスPublished - 2010 4

ASJC Scopus subject areas

  • Oncology
  • Clinical Neurology
  • Cancer Research

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