Maladaptive change of body representation in the brain after damage to central or peripheral nervous system

Yutaka Oouchida, Tamami Sudo, Tetsunari Inamura, Naofumi Tanaka, Yukari Ohki, Shin ichi Izumi

研究成果: Review article査読

19 被引用数 (Scopus)

抄録

Our brain has great flexibility to cope with various changes in the environment. Use-dependent plasticity, a kind of functional plasticity, plays the most important role in this ability to cope. For example, the functional recovery of paretic limb motor movement during post-stroke rehabilitation depends mainly on how much it is used. Patients with hemiparesis, however, tend to gradually disuse the paretic limb because of its motor impairment. Decreased use of the paretic hand then leads to further functional decline brought by use-dependent plasticity. To break this negative loop, body representation, which is the conscious and unconscious information regarding body state stored in the brain, is key for using the paretic limb because it plays an important role in selecting an effector while a motor program is generated. In an attempt to understand body representation in the brain, we reviewed animal and human literature mainly on the alterations of the sensory maps in the primary somatosensory cortex corresponding to the changes in limb usage caused by peripheral or central nervous system damage.

本文言語English
ページ(範囲)38-43
ページ数6
ジャーナルNeuroscience Research
104
DOI
出版ステータスPublished - 2016 3月 1

ASJC Scopus subject areas

  • 神経科学(全般)

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