MagScrew TAH: An update

Stephan Weber, Keiji Kamohara, Ryan S. Klatte, Viviane Luangphakdy, Christine Flick, Ji Feng Chen, Fernando Casas, Yoshio Ootaki, Michael Kopcak, Masatoshi Akiyama, Gordon B. Hirschman, Peter A. Chapman, Arthur Donahue, William Wetterau, Charles Prisco, Roy Mast, Craig Sherman, Kiyotaka Fukamachi, William A. Smith

研究成果: Review article査読

9 被引用数 (Scopus)


The MagScrew Total Artificial Heart (TAH) system is the result of a close collaboration among the Cleveland Clinic Foundation, Foster Miller Technologies, Wilson Greatbatch Ltd, and Whalen Biomedical Inc. The system components are the thoracic blood pumping unit with attached compliance chamber and refill port, implantable electronic control unit, implantable battery pack, transcutaneous energy transmission system, external battery pack, and a telemetry system for communication with the electronic control unit. System in vitro tests are underway for system characterization and durability demonstration, whereas in vivo tests were conducted to evaluate system performance and biocompatibility under physiologic conditions. The passively filling pump uses a left master alternate left and right ejection control mode and has a Starling law-like response to venous pressure. The in vitro tests documented excellent hydraulic pump performance with high device output of over 9 l/min at left atrial pressures below 12 mm Hg. Atrial balance was well maintained under all test conditions. The in vivo tests demonstrated good biocompatibility without use of anticoagulant therapy. Experimental durations have ranged between 0 and 92 days. Postexplant evaluation of tissue samples did not reveal any sign of thromboembolic events or tissue damage due to device operation.

ジャーナルASAIO Journal
出版ステータスPublished - 2005 11月

ASJC Scopus subject areas

  • 生物理学
  • バイオエンジニアリング
  • 生体材料
  • 生体医工学


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