Lysophospholipid mediators: Their receptors and synthetic pathways

Kuniyuki Kano, Kumiko Makide, Jun Ishiguro, Hiroshi Yukiura, Shizu Aikawa, Akiharu Uwamizu, Yuji Shinjo, Kahori Namiki, Hiroki Kawana, Saki Nemoto, Hirotaka Matsumoto, Ryoji Kise, Asuka Inoue, Junken Aoki

研究成果: Chapter

1 被引用数 (Scopus)

抄録

It is now widely accepted that lysophospholipids (LPLs), a product of the phospholipase A reaction, function as mediators through G protein-coupled receptors (GPCRs). Notably, recent studies of lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) have revealed their essential roles in vivo. In addition, recent studies have identified several GPCRs for other lysophospholipids such as lysophosphatidylserine (LysoPS) andlysophosphatidylinositol (LPI). In this chapter, we summarize the actions and production of these LPLs as lipid mediators including LysoPS and LPI.

本文言語English
ホスト出版物のタイトルBioactive Lipid Mediators
ホスト出版物のサブタイトルCurrent Reviews and Protocols
出版社Springer Japan
ページ109-126
ページ数18
ISBN(電子版)9784431556695
ISBN(印刷版)9784431556688
DOI
出版ステータスPublished - 2015 1 1

ASJC Scopus subject areas

  • 生化学、遺伝学、分子生物学(全般)
  • 医学(全般)

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