Lupinacidin C, an inhibitor of tumor cell invasion from micromonospora lupini

Yasuhiro Igarashi, Saeko Yanase, Kohei Sugimoto, Masaru Enomoto, Satoshi Miyanaga, Martha E. Trujillo, Ikuo Saiki, Shigefumi Kuwahara

研究成果: Article

34 引用 (Scopus)

抜粋

A new anthraquinone derivative, lupinacidin C (1), was isolated from the endophytic actinomycete Micromonospora lupini. The structure was elucidated on the basis of spectroscopic analyses, and the absolute configuration was determined by total synthesis. Lupinacidin C (1) exhibited the most potent inhibitory effects among the congeners on the invasion of murine colon carcinoma cells into the reconstituted basement membrane.

元の言語English
ページ(範囲)862-865
ページ数4
ジャーナルJournal of Natural Products
74
発行部数4
DOI
出版物ステータスPublished - 2011 4 25

ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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