Long-term results of definitive treatment in elderly patients with localized prostate cancer

Hiroshi Kanamaru, Yoichi Arai, Seiji Moroi, Hiroshi Yoshida, Koji Yoshimura, Kenichiro Okada

研究成果: Article

9 引用 (Scopus)

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Background: The indication and effectiveness of definitive local treatment for prostate cancer in patients with a limited life expectancy remains to be established. This study is a retrospective analysis of the long-term clinical outcome of elderly patients with localized prostate cancer treated by radiotherapy or a radical prostatectomy. Methods: From 1982 to 1992, 37 patients with localized prostate cancer, aged 70 years or older, were treated initially by a pelvic lymphadenectomy and then with either external radiotherapy (n = 17) or a radical retropubic prostatectomy (n = 20). Lymph node metastasis was negative in all the cases, and no patients received hormonal treatment after the lymphadenectomy. The outcome of all patients was evaluated in June 1997. Results: The 10-year overall and relative survival rates for the radiotherapy group were 27% and 85%, which were not significantly different from the rates of patients in the prostatectomy group (38% and 74%, respectively). The 5-year progression free rates for the radiotherapy group and the prostatectomy group were 63% and 95%, respectively (P = 0.06). Conclusion: In elderly patients with localized prostate cancer, the superiority of a radical prostatectomy over radiotherapy was not demonstrated in terms of either overall or relative survival rates, although the progression rate tended to be higher in patients in the radiotherapy group. The indication of definitive treatment in elderly patients should be further studied incorporating a quality of life assessment.

元の言語English
ページ(範囲)546-549
ページ数4
ジャーナルInternational Journal of Urology
5
発行部数6
DOI
出版物ステータスPublished - 1998
外部発表Yes

ASJC Scopus subject areas

  • Urology

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