Lectin histochemistry in adrenocortical hyperplasia and neoplasms with emphasis on carcinoma

H. Sasano, Masato Nose, N. Sasano

研究成果: Article査読

10 被引用数 (Scopus)

抄録

Lectin binding analysis of Con A, SBA, PNA, WGA, HPA, RCA-I, DBA and UEA-I was performed in two cases of normal human adrenal gland, four cases of adrenocortical hyperplasia, six cases of adrenocortical adenoma, and seven cases of adrenocortical carcinoma to examine the differences of lectin binding properties. No lectins were bound specifically to adrenocortical cells. Binding of RCA-I was observed in some carcinoma cells focally but not in benign counterparts. With WGA and Con A, the cytoplasmic binding became apparent in the cells manifesting hypercorticism. In adrenocortical carcinoma, various WGA and Con A binding patterns were intermingled, but no specific patterns were identified. The focal nature of RCA-I binding, and no specific WGA and Con A binding properties in carcinoma, suggest that diagnosis of malignant neoplasm must still largely rely on clinical, hormonal, and structural criteria in adrenocortical neoplasms.

本文言語English
ページ(範囲)68-72
ページ数5
ジャーナルArchives of Pathology and Laboratory Medicine
113
1
出版ステータスPublished - 1989 1 1

ASJC Scopus subject areas

  • 病理学および法医学
  • 医療検査技術

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