Lectin cytochemical analysis of lacrimal pleomorphic adenomas

Kuri Motegi, Makoto Ishikawa, Tohru Abe, Ryuko Nakayama, Shozo Sakuragi

研究成果: Article査読

抄録

The activity of seven different types of biotinylated lectin were examined in normal and tumorous lacrimal gland tissue. In the normal lacrimal gland tissue, the glandular cells and the tubular epithelium were labeled by maclura pomifera agglutinin (MPA), soybean agglutinin (SBA), and bauhinia purpurea agglutinin (BPA). The myoepithelial cells were stained by griffonia simplicifolia agglutinin 1 (GS1). In the primary pleomorphic adenoma tissue, the epithelial components were labeled by MPA, ulex europaeus agglutinin, SBA, peanut agglutinin, and BPA. The mesenchymal components showed negative labeling. In contrast, the recurrent pleomorphic adenoma tissue showed a positive reaction in the mesenchymal components when GS1 and BPA were used. These results revealed differences in the glycoconjugate composition among normal and tumorous lacrimal gland tissues from patients with primary and recurrent pleomorphic adenomas.

本文言語English
ページ(範囲)249-255
ページ数7
ジャーナルJapanese Journal of Ophthalmology
42
4
DOI
出版ステータスPublished - 1998 7月
外部発表はい

ASJC Scopus subject areas

  • 眼科学

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