Intracellular Electrochemical Sensing

Kosuke Ino, Yuji Nashimoto, Noriko Taira, Javier Ramon Azcon, Hitoshi Shiku

研究成果: Review article査読

12 被引用数 (Scopus)

抄録

Observing biochemical processes within living cell is imperative for biological and medical research. Fluoresce imaging is widely used for intracellular sensing of cell membranes, nuclei, lysosomes, and pH. Electrochemical assays have been proposed as an alternative to fluorescence-based assays because of excellent analytical features of electrochemical devices. Notably, thanks to the rapid progress of micro/nanotechnologies and electrochemical techniques, intracellular electrochemical sensing is making rapid progress, leading to a successful detection of intracellular components. Such insight can provide a deep understanding of cellular biological processes and, ultimately, define the human healthy and diseased states. In this review, we present an overview of recent research progress in intracellular electrochemical sensing. We focus on two main topics, electrochemical extraction of cytosolic contents from cells and intracellular electrochemical sensing in situ.

本文言語English
ページ(範囲)2195-2209
ページ数15
ジャーナルElectroanalysis
30
10
DOI
出版ステータスPublished - 2018 10
外部発表はい

ASJC Scopus subject areas

  • 分析化学
  • 電気化学

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