Interaction of inorganic mercury and selenite in rabbit blood after intravenous administration

Nobumasa Imura, Akira Naganuma

研究成果: Article査読

25 被引用数 (Scopus)

抄録

Behaviors of selenite and inorganic mercury and interaction of these compounds in rabbit blood were investigated after intravenous administration. The major portion of the materials, when administered alone, was initially present in the plasma, but the plasma levels decreased rapidly. Simultaneous administration of both compounds caused the elevation of their levels in the erythrocyte. The radioactivity of both mercury and selenium in the erythrocyte showed relatively slow decay during the experiment, while that in the plasma decreased rapidly after a short stable phase of about one hour. Sephadex column chromatography of the stroma free hemolysate indicated an identical pattern of distribution of mercury and selenium as that observed in an in vitro study.

本文言語English
ページ(範囲)67-73
ページ数7
ジャーナルjournal of pharmacobio-dynamics
1
2
DOI
出版ステータスPublished - 1978 1 1

ASJC Scopus subject areas

  • Pharmacology

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