Inhibition of F-box protein FBXO6 gene expression by RNA interference enhances cadmium toxicity in HEK293 cells

Gi Wook Hwang, Ke Du, Tsutomu Takahashi, Akira Naganuma

研究成果: Article査読

7 被引用数 (Scopus)

抄録

Cadmium is a typical environmental pollutant and the causative agent of itai-itai disease. Ubiquitin ligases potentially involved in mediating the effects of cadmium toxicity were investigated by RNA interference using a panel of small inhibitory (si)RNAs. The results demonstrated that the inhibition of gene expression of FBXO6 sensitizes HEK293 cells to cadmium.

本文言語English
ページ(範囲)847-849
ページ数3
ジャーナルJournal of Toxicological Sciences
36
6
DOI
出版ステータスPublished - 2011

ASJC Scopus subject areas

  • 毒物学

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