Influence of the Maillard Reaction on the Allergenicity of Food Proteins and the Development of Allergic Inflammation

Masako Toda, Michael Hellwig, Thomas Henle, Stefan Vieths

研究成果: Review article査読

9 被引用数 (Scopus)

抄録

Purpose of Review: The Maillard reaction (MR) is a non-enzymatic reaction between reducing sugars and compounds with free amino groups such as proteins and takes place during thermal processing and storage of foods. This review aims to discuss potential effects of dietary MR products on the pathological mechanisms of allergic diseases. Recent Findings: Since the MR leads to modification of proteins with various types of glycation structures, the impact of the MR on the immunogenicity and potential allergenicity of food proteins in many allergenic foods has been assessed. In addition, recent studies have suggested that the MR products, in particular “advanced glycation end products (AGEs),” contained in the diet may be involved in the development of chronic inflammation by acting as inflammatory components and affecting the gut microbiome. Summary: This review found that the biological, immunological, and allergic properties of dietary MR products are diverse due to the complexity of the MR.

本文言語English
論文番号4
ジャーナルCurrent Allergy and Asthma Reports
19
1
DOI
出版ステータスPublished - 2019 1 1

ASJC Scopus subject areas

  • 免疫アレルギー学
  • 免疫学
  • 呼吸器内科

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