Influence of plaque stiffness on change of blood vessel geometry leading hemodynamical changes in PVA-H stenosis models

Yasutomo Shimizu, Shuya Shidam, Kenichi Funamoto, Toshiyuki Hayase, Makoto Ohta

研究成果: Conference contribution

3 被引用数 (Scopus)

抄録

One of the main factors affecting blood flow conditions in stenotic arteries is plaque geometry. Plaques can be deformed by the internal pressure, and hence plaque behavior varies depending on its stiffness. Blood flow pattern around a plaque is complicated by plaque behavior, and these complications may lead to growth of the plaque itself. Thus, we can say that geometry and mechanical properties of a plaque, and blood flow will affect each other. To understand the relationship between plaque stiffness and flow pattern, flow measurement using elastic models, which mimic the mechanical properties of blood vessels, is required. Flow patterns with steady flows and a range of hydrostatic pressures were observed by particle image velocimetry. The results show that the model is deformed by hydrostatic pressures. Furthermore, flow patterns are also changed as the results of model deformation, especially at reattachment points. Simultaneously, we performed a numerical simulation for finding a critical parameter of the flow patterns. These results show that the reattachment length increases in the model with high stenosis severity and in a vertically oriented parent artery. In conclusion, a parent artery and plaque can deform because of internal pressure, and these deformation will affect blood flow patterns.

本文言語English
ホスト出版物のタイトルASME 2012 International Mechanical Engineering Congress and Exposition, IMECE 2012
ページ455-460
ページ数6
DOI
出版ステータスPublished - 2012 12 1
イベントASME 2012 International Mechanical Engineering Congress and Exposition, IMECE 2012 - Houston, TX, United States
継続期間: 2012 11 92012 11 15

出版物シリーズ

名前ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)
2

Other

OtherASME 2012 International Mechanical Engineering Congress and Exposition, IMECE 2012
国/地域United States
CityHouston, TX
Period12/11/912/11/15

ASJC Scopus subject areas

  • 機械工学

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