Induction of HSP90α heat shock mRNA after transient global ischemia in gerbil hippocampus

Jun ichi Kawagoe, Koji Abe, Masashi Aoki, Kyuya Kogure

研究成果: Article査読

32 被引用数 (Scopus)

抄録

Distribution of heat shock protein (HSP) 90α mRNA induction after 10 min of transient global ischemia was investigated in gerbil hippocampus by in situ hybridization. A small amount of HSP90α mRNA was normally present in hippocampal cells and the mRNA was further induced with a peak at 8 h after ischemia. In hippocampal CA1 cells that are vulnerable to ischemia, HSP90α mRNA was continuously induced by 1 day and finally diminished at 2 days. The temporal profile of HSP90α mRNA induction in hippocampal CA1 cells was similar to that of HSP70 mRNA reported previously, suggesting a cooperative role of HSP90α with other HSPs after ischemia.

本文言語English
ページ(範囲)121-125
ページ数5
ジャーナルBrain research
621
1
DOI
出版ステータスPublished - 1993 9 3

ASJC Scopus subject areas

  • 神経科学(全般)
  • 分子生物学
  • 臨床神経学
  • 発生生物学

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