Incidence of fungi isolated from 505 clinical specimens investigated. The annual incidence was 36.5% in '89, 25.9% in '90 and 14.8% in '91. Candida albicans was isolated from 249 (49.3%) of total specimens. Among other Candida spp., Candida glabrata and Candida tropicalis were isolated from 66 (13.1%) and 41 (8.2%) strains, respectively. Aspergillus fumigatus and Cryptococcus neoformans were isolated from 29 (5.7%) and 27 strains (5.3%), respectively. The number of samples from which fungi were isolated in each specimen were 23/33 in stool, 21/31 in pharynx swab, 255/376 in sputum, 5/71 in plugged catheter brush, 28/423 in blood (lysis centrifugation) and 27/495 in blood (BCB bottle). From tongue coating, pharynx swab, and sputum, Candida albicans was the most frequently isolated fungus. The isolation rate of Cryptococcus neoformans in TBLB and Aspergillus spp. in percutaneous aspirate were the highest in all specimens. The number of fungi isolated from specimens obtained from patients with fungal infections was determined. The ratio of samples cultured with Candida spp. in blood (lysis method) was the highest (95.7%) in candidemia. The isolation rates of fungi in sputum from patients with pulmonary aspergilloma and pulmonary cyptococcosis were 66.7% and 50%, respectively.
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