Impact of diabetes mellitus on rehospitalization for heart failure among survivors of acute myocardial infarction in the percutaneous coronary intervention era

Daisaku Nakatani, Yasuhiko Sakata, Hiroya Mizuno, Masahiko Shimizu, Shinichiro Suna, Masaya Usami, Hiroshi Ito, Yoshio Yasumura, Atsushi Hirayama, Hiroshi Takeda, Masatsugu Hori, Hiroshi Sato

研究成果: Article査読

15 被引用数 (Scopus)

抄録

Background: There is little data regarding the clinical impact of diabetes mellitus (DM) on heart failure (HF) among survivors of acute myocardial infarction (AMI) in the percutaneous coronary intervention (PCI) era. Methods and Results: The present study group comprised 4,035 survivors who underwent PCI within 24 h of the onset of symptoms. DM was an independent predictor of rehospitalization for HF by multivariate analysis (hazard ratio (HR) 1.576, P=0.010). The risk of rehospitalization for HF was similar between patients with DM who did not have an enlarged left vetricular diastolic diameter (LVDd <51 mm) before discharge and patients without DM who showed an increase in LVDd (≥51 mm) (HR 1.020, P=0.959). In the DM group, the hemoglobin A1c level before discharge was similar between patients with and without rehospitalization for HF (7.5±1.9% vs 7.4±1.6%, P=0.455), whereas high-sensitivity C-reactive protein (hs-CRP) was higher in patients with than without rehospitalization for HF (1.80±3.63 vs 0.75±2.03 mg/dl, P=0.001). Conclusions: DM is an independent predictor of rehospitalization for HF after AMI in the PCI era. Diabetic patients without left ventricular remodeling should be treated as a high-risk group for HF. Measurement of hs-CRP level may be useful for predicting rehospitalization because of HF in diabetic patients after AMI.

本文言語English
ページ(範囲)662-666
ページ数5
ジャーナルCirculation Journal
73
4
DOI
出版ステータスPublished - 2009 4
外部発表はい

ASJC Scopus subject areas

  • 循環器および心血管医学

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