Identification of two teleost homologs of the Drosophila sex determination factor, transformer-2 in medaka (Oryzias latipes)

Eri Shiraishi, Hideo Imazato, Takashi Yamamoto, Hayato Yokoi, Shin Ichi Abe, Takeshi Kitano

研究成果: Article査読

9 被引用数 (Scopus)

抄録

Transformer-2 (Tra2), an RNA-binding protein, is an important regulator in Drosophila sex determination. In vertebrates, however, the role of Tra2 homologues is not known. We identified two teleost homologues of Tra2, which we named Tra2a and Tra2b, in medaka (Oryzias latipes). Furthermore, we demonstrated that both Tra2 mRNAs were predominantly expressed in germ cells of both sexes before the onset of sex differentiation, suggesting that both Tra2 homologues might be involved in the sex differentiation in medaka.

本文言語English
ページ(範囲)991-996
ページ数6
ジャーナルMechanisms of Development
121
7-8
DOI
出版ステータスPublished - 2004 7
外部発表はい

ASJC Scopus subject areas

  • 胎生学
  • 発生生物学

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