Identification of the Marek's Disease Virus Serotype 2 Genes Homologous to the Glycoprotein B (UL27), ICP18.5 (UL28) and Major DNA-Binding Protein (UL29) Genes of Herpes Simplex Virus Type 1

Kentaro Kato, Hyung Kwan Jang, Yoshihiro Izumiya, Jin Shun Cai, Yoshinori Tsushima, Takayuki Miyazawa, Chieko Kai, Takeshi Mikami

研究成果: Article査読

8 被引用数 (Scopus)

抄録

We determined the nucleotide sequence of non-pathogenic Marek's disease virus serotype 2 (MDV2) strain HPRS24 glycoprotein B (gB) (UL27), ICP18.5 (UL28) and major DNA-binding protein (MDBP) (UL29) genes homologous to herpes simplex virus type 1 (HSV-1). The sequence data revealed that important motives in the proteins are conserved in MDV2 ICP 18.5 and MDBP, however the sequence of viral DNA replication origin which exists in the regions between the UL29 and UL30 genes of other alphaherpesviruses was not found in the regions of the MDV2 genome. By northern blot analyses, we also demonstrated that 8.9, 5.0 and 2.6 kb transcripts were actually transcribed from the sequenced region in MDV2-infected cells. The MDV2 UL28 and UL29 genes have not been reported in other scrotypes of MDV.

本文言語English
ページ(範囲)1161-1165
ページ数5
ジャーナルJournal of Veterinary Medical Science
61
10
出版ステータスPublished - 1999 10 1
外部発表はい

ASJC Scopus subject areas

  • 獣医学(全般)

フィンガープリント

「Identification of the Marek's Disease Virus Serotype 2 Genes Homologous to the Glycoprotein B (UL27), ICP18.5 (UL28) and Major DNA-Binding Protein (UL29) Genes of Herpes Simplex Virus Type 1」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

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