Identification and Sequence of Seventy-nine New Transcripts Expressed in Hemocytes of Ciona intestinalis, Three of Which May Be Involved in Characteristic Cell-cell Communication

Daichi Terajima, Shigeyuki Yamada, Ryuji Uchino, Shuntaro Ikawa, Makoto Ikeda, Kazuhito Shida, Yoichi Arai, Hong Gang Wang, Nori Satoh, Masanobu Satake

研究成果: Article査読

20 被引用数 (Scopus)

抄録

Ascidian is a useful experimental animal for studying body planning principles and host defense mechanisms employed by the phylum chordata. Toward this goal, genome and cDNA/EST projects of Ciona intestinalis have been undertaken. Using cDNAs and ESTs derived from Ciona hemocytes, we identified 79 possible hemocyte-preferential transcripts and determined the cDNA sequence of each clone. The amino acid sequence of each encoded polypeptide was predicted as well. Among these cDNAs, we identified three transcripts that may be involved in characteristic cell-cell communication in Ciona. These transcripts encoded leucine-rich repeat-containing RP105-like, IL-17 receptor/similar expression to FGF-like, and ectodysplasin-like polypeptide of the tumor necrosis factor family, and they are expressed abundantly in hemocytes.

本文言語English
ページ(範囲)203-212
ページ数10
ジャーナルDNA Research
10
5
DOI
出版ステータスPublished - 2003

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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