Hydroxyapatite-forming ability and mechanical properties of organic-inorganic hybrids reinforced by calcium phosphates

Tomohiro Uchino, Chikara Ohtsuki, Masanobu Kamitakahara, Masao Tanihara, Toshiki Miyazaki

研究成果: Article査読

4 被引用数 (Scopus)

抄録

The bone-bonding ability, known as bioactivity, of ceramic biomaterials is usually evaluated by the potential for hydroxyapatite (HAp) formation on their surfaces after exposure to a simulated body fluid (SBF) proposed by Kokubo et al. We previously reported that an organic-inorganic hybrid synthesized from 2-hydroxy-ethylmethacrylate and 3-methacryloxypropyltrimethoxysilane showed formation of HAp on its surface in SBF, when calcium ions were incorporated into the hybrid. In the present study, the hybrid was combined with α-tricalcium phosphate porous body or calcium phosphates powder (CPP) consisting of dicalcium phosphate anhydrous and tetracalcium phosphate as the Ca2+ sources, to improve the mechanical strength of the hybrid. These composites formed HAp on their surfaces in SBF. The mechanical strength of the hybrid was improved by the reinforcement with calcium phosphates. When CPP was used, the compressive strength of the composite increased after soaking in SBF for one day. The combination of the hybrid and calcium phosphates offers a novel design for bioactive materials.

本文言語English
ページ(範囲)692-696
ページ数5
ジャーナルJournal of the Ceramic Society of Japan
114
1332
DOI
出版ステータスPublished - 2006
外部発表はい

ASJC Scopus subject areas

  • セラミックおよび複合材料
  • 化学 (全般)
  • 凝縮系物理学
  • 材料化学

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