Hydration of single-stranded DNA in water studied by infrared spectroscopy

Ko ichiro Miyamoto, Kota Onodera, Ryo taro Yamaguchi, Ken ichi Ishibashi, Yasuo Kimura, Michio Niwano

研究成果: Article査読

10 被引用数 (Scopus)

抄録

Hydration of single-stranded DNAs (oligonucleotides) of thymine (dT10) and adenine (dA10) in heavy water has been investigated using infrared absorption spectroscopy in the geometry of multiple internal reflection. Comparison of infrared absorption data with results of ab initio cluster calculation clearly indicates that water molecules are bound to the C{double bond, long}O and N-H bonds of the thymine base, giving rise to a red-shift of the C{double bond, long}O stretching vibration modes, and that the water molecule is site-specifically bound to the thymine base. We find that hydration induces a blue-shift of the ring deformation mode of the adenine base.

本文言語English
ページ(範囲)233-238
ページ数6
ジャーナルChemical Physics Letters
436
1-3
DOI
出版ステータスPublished - 2007 2 27

ASJC Scopus subject areas

  • 物理学および天文学(全般)
  • 物理化学および理論化学

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