Human REG family genes are tandemly ordered in a 95-kilobase region of chromosome 2p12

Hikari Miyashita, Kan ichi Nakagawara, Mitsuko Mori, Yoichi Narushima, Naoya Noguchi, Shigeki Moriizumi, Shin Takasawa, Hideto Yonekura, Takuji Takeuchi, Hiroshi Okamoto

研究成果: Article査読

40 被引用数 (Scopus)

抄録

Reg, first isolated from a rat regenerating islet cDNA library, is expressed in regenerating islet β-cells. Recently, it has been revealed that Reg and Reg-related genes constitute a multigene family, the Reg family. In human, the four REG family genes, i.e., REG Iα, REG Iβ, REG-related sequence (RS) and HIPIPAP, have so far been isolated. In this study, we analyzed YAC clones containing the four genes and performed two-color FISH to determine the map order of the genes. The human REG family genes are tandemly ordered in the 95-kbp DNA region of chromosome 2p12 as follows: 2cen-HIPIPAP-RS-REG Iα-REG Iβ-ptel.

本文言語English
ページ(範囲)429-433
ページ数5
ジャーナルFEBS Letters
377
3
DOI
出版ステータスPublished - 1995 12 27

ASJC Scopus subject areas

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology

フィンガープリント 「Human REG family genes are tandemly ordered in a 95-kilobase region of chromosome 2p12」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル