How a nerve fiber repairs its cut end: Involvement of phospholipase A 2

Hiromu Yawo, Motoy Kuno

    研究成果: Article査読

    100 被引用数 (Scopus)

    抄録

    Following transection of a giant axon, the nerve membrane at the cut end is resealed within 5 to 30 minutes. This membrane resealing process is highly dependent upon temperature and extracellular calcium ions. The membrane resealing is triggered by excess calcium entering the axoplasm at the site of transection but is prevented by the application of phospholipase A2 inhibitors. We propose that calcium activated phospholipase A2 plays a central role in resealing of the ruptured nerve membrane.

    本文言語English
    ページ(範囲)1351-1353
    ページ数3
    ジャーナルScience
    222
    4630
    DOI
    出版ステータスPublished - 1983 1 1

    ASJC Scopus subject areas

    • 一般

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