For the purpose of the ophthalmology treatment a special hollow waveguide based delivery instrument was developed. It consists of a 2 m long cyclic olefin polymer coated silver hollow glass waveguide (inner diameter 700 μm) and the special cap allowing the contact of the waveguide with the wet eye tissue. The transmission characteristics for a delivery of a mid-infrared Er:YAG laser radiation (λ=2.94 μm) was measured. Then the pre-clinical interaction experiments of the Er:YAG laser radiation with the eye tissues (cornea, lens, and sclera) were performed with this delivery instrument. A comparison of two types of interactions results - the action of Er:YAG free running pulses (with length 40 μs) and giant pulses (450 ns FWHM) were investigated. The human eye tissues (in vitro) were cut and samples (cornea, lens, and sclera) were gradually irradiated by radiation with the energy of 7 mJ (the corresponding spot size diameter was equal ∼ 700 μm). The Er:YAG laser fluence used in this experiment was 1.8 J/cm2. From the results it can be concluded that the giant pulses are more efficient in the ablation of the cornea, they are comparable with the free-running long pulses in the case of lens grinding, and they are less functioning for the sclera perforation. As concern the hollow waveguide delivery system, it has been proved that the energy delivered by this system was sufficient and suitable for delivery of long - free-running pulses and short - giant pulses, as well.
|ジャーナル||Proceedings of SPIE - The International Society for Optical Engineering|
|出版ステータス||Published - 2003 12 5|
|イベント||PROGRESS IN BIOMEDICAL OPTICS AND IMAGING: Optical Fibers and Sensors for Medical Applications III - San Jose, CA, United States|
継続期間: 2003 1 25 → 2003 1 28
ASJC Scopus subject areas
- コンピュータ サイエンスの応用