Histological study of effect of bone morphogenetic protein derived from bovine tooth on periosteum in rats

Masatoshi Chiba, Takashi Shigihara, Seishi Echigo, Teiichi Teshima

研究成果: Article査読

1 被引用数 (Scopus)

抄録

In this study, we examined histologically the effect of a bone morphogenetic protein (BMP) derived from bovine tooth on the periosteum. Supraperiosteal injection of crude BMP into femurs of Wistar rats (28 day old) resulted in periosteal cell proliferation with subsequent bone and cartilage formation. Moreover, proliferating periosteal cells migrated into injected BMP, and formed both cartilage and bone. These observations show that exogenous BMP stimulates mesenchymal cells of the periosteum to proliferate and differentiate into osteoblasts, and therefore BMP may be one of factors which are involved in differentiation of osteoblasts in the periosteum.

本文言語English
ページ(範囲)24-29
ページ数6
ジャーナルJournal of Bone and Mineral Metabolism
8
3
DOI
出版ステータスPublished - 1990 12 1

ASJC Scopus subject areas

  • 内分泌学、糖尿病および代謝内科学
  • 整形外科およびスポーツ医学
  • 内分泌学

フィンガープリント

「Histological study of effect of bone morphogenetic protein derived from bovine tooth on periosteum in rats」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル