Highly diastereoselective construction of acyclic systems with two adjacent quaternary stereocenters by allylation of ketones

Takeshi Takeda, Masanori Yamamoto, Satoshi Yoshida, Akira Tsubouchi

研究成果: Article査読

25 被引用数 (Scopus)

抄録

Unsymmetrical ketones and allyltitanocenes generated by the desulfurizative titanation of -disubstituted allyl phenyl sulfides react under highly diastereoselective construction of adjacent quaternary stereocenters (see scheme; R L=large group, R S=small group). The title reaction is stereospecific: the anti- and syn-homoallylic alcohols are obtained by the reaction of E- and Z-allylic sulfides, respectively.

本文言語English
ページ(範囲)7263-7266
ページ数4
ジャーナルAngewandte Chemie - International Edition
51
29
DOI
出版ステータスPublished - 2012 7 16
外部発表はい

ASJC Scopus subject areas

  • 触媒
  • 化学 (全般)

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