Highly diastereo- and enantioselective direct aldol reactions in water

Yujiro Hayashi, Tatsunobu Sumiya, Junichi Takahashi, Hiroaki Gotoh, Tatsuya Urushima, Mitsuru Shoji

研究成果: Article査読

446 被引用数 (Scopus)

抄録

(Chemical Equation Presented) Going green: The synthetically very important aldol reaction can proceed in water without a metal catalyst with excellent enantioselectivity. The key to the reaction is a small, synthetic organic catalyst based on trans-hydroxyproline with a siloxy group. Thus, this method is an environmentally friendly process for the synthesis of chiral molecules.

本文言語English
ページ(範囲)958-961
ページ数4
ジャーナルAngewandte Chemie - International Edition
45
6
DOI
出版ステータスPublished - 2006 1 30
外部発表はい

ASJC Scopus subject areas

  • 触媒
  • 化学 (全般)

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