High salt concentrations increase permeability through ompc channels of escherichia coli

Seiji Kojima, Hiroshi Nikaido

研究成果: Article査読

34 被引用数 (Scopus)

抄録

Background: OmpC porin is less permeable than OmpF, but there is little difference in channel size.

Results: There are more charged residues in the OmpC channel, and mutating them or increasing ionic strength made it more permeable and OmpF-like.

Conclusion: Charged residues produce the low permeability of OmpC.

Significance: OmpC, produced in a high ionic strength environment, has properties optimized for this environment.

本文言語English
ページ(範囲)26464-26473
ページ数10
ジャーナルJournal of Biological Chemistry
289
38
DOI
出版ステータスPublished - 2014 9 19
外部発表はい

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

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