High rate of small TP53 mutations and infrequent loss of heterozygosity in malignant liver tumors associated with Thorotrast: Implications for alpha- particle carcinogenesis

Medicine and Dentistry

• Hepatocellular Carcinoma 100%
• Heterozygosity 80%
• Thorium Dioxide 80%
• Liver Tumor 60%
• Angiosarcoma 60%
• Gene 60%
• Cholangiocarcinoma 40%
• Exon 40%
• Carcinogenesis 40%
• Autopsy 20%
• Protein P53 20%
• Necrosis 20%
• Intron 20%
• Point Mutation 20%
• Regeneration 20%
• Malignant Neoplasm 20%
• Single Strand Conformation Polymorphism 20%
• Injection 20%
• Thinking 20%
• Analysis 20%
• Tissues 20%
• Cancer 20%

Biochemistry, Genetics and Molecular Biology

• Loss of Heterozygosity 80%
• Nested Gene 60%
• Mutation 60%
• Carcinogenesis 40%
• Gene Mutation 40%
• Intron 20%
• Single-Strand Conformation Polymorphism 20%
• Point Mutation 20%
• Regeneration 20%
• P53 20%
• Transversion 20%
• Light 20%
• Alpha Radiation 20%
• Thinking 20%
• Sequencing 20%

Veterinary Science and Veterinary Medicine

• Angiosarcoma 60%
• Liver 40%
• P53 20%