High performance optical resolution with liposome immobilized hydrogel

Takaaki Ishigami, Kazuma Sugita, Keishi Suga, Yukihiro Okamoto, Hiroshi Umakoshi

研究成果: Article査読

6 被引用数 (Scopus)

抄録

We prepared liposome immobilized hydrogels (LI-gels) for analysis and separation of chiral molecules, to overcome the drawbacks of liposomes such as low stability, and difficulties with handling and isolation from sample solutions. The amounts of liposomes in the hydrogels were larger than those in other solid matrices reported previously. The liposome morphology was intact, and its original properties, such as fluidity and phase transition behaviors, were preserved. We investigated the chiral recognition performance of the LI-gel, as described in our previous paper. Our results indicate that the enantioselectivity of the LI-gel was higher than those of conventional methods and of the liposomes alone. Our prepared LI-gel therefore overcomes the drawbacks of liposomes, and has potential applications in analysis and separation, including chiral separation.

本文言語English
ページ(範囲)256-261
ページ数6
ジャーナルColloids and Surfaces B: Biointerfaces
136
DOI
出版ステータスPublished - 2015 12 1
外部発表はい

ASJC Scopus subject areas

  • Biotechnology
  • Surfaces and Interfaces
  • Physical and Theoretical Chemistry
  • Colloid and Surface Chemistry

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