Haemodynamics and oxygen metabolism in patients after reversible ischaemic attack or minor ischaemic stroke assessed with positron emission tomography

M. Itoh, J. Hatazawa, C. Pozzilli, H. Fukuda, Y. Abe, T. Fujiwara, K. Kubota, K. Yamaguchi, T. Sato, H. Watanabe, T. Ido, T. Matsuzawa

研究成果: Article査読

11 被引用数 (Scopus)

抄録

Regional cerebral blood flow (CBF), blood volume (CBV) and oxygen metabolic rate (CMRO2) were evaluated and compared among normals, patients with recent reversible ischaemic attacks (RIAs) and patients with chronic minor infarction using positron emission tomography. Average CBF together with CMRO2 significantly decreased in the infarction group in the middle cerebral artery territory of the affected hemisphere while the mean values for RIAs were intermediate between the other two groups. CBV also reduced, however it was more preserved compared to flow as seen in decreased CBF/CBV values. Significant interhemispheric difference was found in CBF/CBV ratio, but it did not clearly correlate with OEF changes. Higher OEF was noted only in the restricted brain regions of RIAs where CBF showed large hemispheric asymmetry. However, in other regions, the coupled decline of blood flow and metabolism was found which suggests tissue damage or neuronal cell loss in the brain with previous RIA symptoms.

本文言語English
ページ(範囲)416-421
ページ数6
ジャーナルNeuroradiology
29
5
DOI
出版ステータスPublished - 1987 9月

ASJC Scopus subject areas

  • 放射線学、核医学およびイメージング
  • 臨床神経学
  • 循環器および心血管医学

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