Giant cell tumor of fifth lumbar vertebrae: two case reports and review of the literature

Yoichi Shimada, Michio Hongo, Naohisa Miyakoshi, Yuji Kasukawa, Shigeru Ando, Eiji Itoi, Eiji Abe

研究成果: Article査読

37 被引用数 (Scopus)

抄録

Background context: complete or total en bloc spondylectomy has been recommended for giant cell tumors of the spine. Wide local resection of the fifth lumbar vertebra carries potential risks of major complications because of its anatomical features. Only nine cases of the giant cell tumors involving the fifth lumbar vertebra have been reported in the literature. Purpose: to present two cases of giant cell tumor of the fifth lumbar vertebra treated by single-stage combined anterior and posterior tumor resection over 7 years of follow-up. Study design: Case report and a review of literature. Methods: A 33-year-old female and a 20-year-old female, each diagnosed with giant cell tumor of fifth lumbar vertebra, underwent single-stage tumor resection through a combined posterior and retroperitoneal anterior approach. Results: The resection of the fifth lumbar vertebra was completed in the first case without major perioperative complications. In the second case, massive bleeding during the anterior procedure for resection of the vertebral body interrupted the total resection of the tumor, resulting in possible residual tumor which required adjuvant radiotherapy. The patients recovered both clinically and neurologically after the operation. Spinal reconstruction was maintained, and no recurrence of the tumor was evident at the 7-year and 8-year follow-up, respectively. Conclusion: There was no recurrence of the tumor after the combined single-stage anterior and posterior tumor resection and adjuvant radiotherapy for the second case for over 7 years follow-up. However, complete resection of the vertebra and tumor at the fifth lumbar vertebra is still challenging to accomplish.

本文言語English
ページ(範囲)499-505
ページ数7
ジャーナルSpine Journal
7
4
DOI
出版ステータスPublished - 2007 7月
外部発表はい

ASJC Scopus subject areas

  • 外科
  • 整形外科およびスポーツ医学
  • 臨床神経学

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