@article{49f1ec09173e4431b1c26f04c4a13bf3,
title = "Genotyping of single nucleotide polymorphisms (SNPs) influencing drug response by competitive allele-specific short oligonucleotide hybridization (CASSOH) with immunochromatographic strip.",
abstract = "Using competitive allele-specific oligonucleotide hybridization with immunochromatographic strip (CASSOH), we have developed a simplified method for the detection of eight polymorphisms that are especially important in the identification of drug responders or non-responders and patients at increased risk of drug toxicity. The genotyping method is unambiguously determined by the presence or the absence of visible purple lines on the immunochromatographic strip, and results are obtained within 5 min after PCR. This method is rapid, highly sensitive, simplified, and should be suitable for point-of-care genotyping in clinical settings.",
author = "Masahiro Hiratsuka and Aiko Ebisawa and Yoichi Matsubara and Shigeo Kure and Yumiko Konno and Takamitsu Sasaki and Michinao Mizugaki",
note = "Funding Information: Acknowledgements: This work was supported in parts by a Grant-in-Aid for Research on Sensory and Communicative Disorders from the Ministry of Health, Labor and Welfare of Japan; a Grant-in Aid for Young Scientists (B) from the Japan Society for the Promotion of Science; the Takeda Science Foundation; the Mochida Memorial Foundation for Medical and Pharmaceutical Research; and the Research Foundation for Pharmaceutical Sciences.",
year = "2004",
month = aug,
doi = "10.2133/dmpk.19.303",
language = "English",
volume = "19",
pages = "303--307",
journal = "Drug Metabolism and Pharmacokinetics",
issn = "1347-4367",
publisher = "Japanese Society for the Study of Xenobiotics",
number = "4",
}