Genomic and serological detection of bat coronavirus from bats in the Philippines

Shumpei Tsuda, Shumpei Watanabe, Joseph S. Masangkay, Tetsuya Mizutani, Phillip Alviola, Naoya Ueda, Koichiro Iha, Satoshi Taniguchi, Hikaru Fujii, Kentaro Kato, Taisuke Horimoto, Shigeru Kyuwa, Yasuhiro Yoshikawa, Hiroomi Akashi

研究成果: Article査読

17 被引用数 (Scopus)

抄録

Bat coronavirus (BtCoV) is assumed to be a progenitor of severe acute respiratory syndrome (SARS)-related coronaviruses. To explore the distribution of BtCoVs in the Philippines, we collected 179 bats and detected viral RNA from intestinal or fecal samples by RT-PCR. The overall prevalence of BtCoVs among bats was 29.6 %. Phylogenetic analysis of the partial RNA-dependent RNA polymerase gene suggested that one of the detected BtCoVs was a novel alphacoronavirus, while the others belonged to the genus Betacoronavirus. Western blotting revealed that 66.5 % of bat sera had antibodies to BtCoV. These surveys suggested the endemic presence of BtCoVs in the Philippines.

本文言語English
ページ(範囲)2349-2355
ページ数7
ジャーナルArchives of virology
157
12
DOI
出版ステータスPublished - 2012 12
外部発表はい

ASJC Scopus subject areas

  • ウイルス学

フィンガープリント

「Genomic and serological detection of bat coronavirus from bats in the Philippines」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル