Genomic analysis of DUSP6, a dual specificity MAP kinase phosphatase, in pancreatic cancer

T. Furukawa, T. Yatsuoka, E. M. Youssef, T. Abe, T. Yokoyama, S. Fukushige, E. Soeda, M. Hoshi, Y. Hayashi, M. Sunamura, M. Kobari, A. Horii

研究成果: Article査読

67 被引用数 (Scopus)

抄録

DUSP6 (alias PYST1), one of the dual-specificity tyrosine phosphatases, is localized on 12q21, one of the regions of frequent allelic loss in pancreatic cancer. This gene is composed of three exons, and two forms of alternatively spliced transcripts are ubiquitously expressed. Although no mutations were observed in 26 pancreatic cancer cell lines, reduced expressions of the full-length transcripts were observed in some cell lines, which may suggest some role for DUSP6 in pancreatic carcinogenesis.

本文言語English
ページ(範囲)156-159
ページ数4
ジャーナルCytogenetics and Cell Genetics
82
3-4
DOI
出版ステータスPublished - 1998

ASJC Scopus subject areas

  • 遺伝学
  • 細胞生物学

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