Genome-wide demethylation during neural differentiation of P19 embryonal carcinoma cells

Izuho Hatada, Sumiyo Morita, Mika Kimura, Takuro Horii, Riu Yamashita, Kenta Nakai

研究成果: Article

14 引用 (Scopus)

抜粋

Epigenetic regulation including DNA methylation plays an important role in several differentiation processes. We profiled global DNA methylation in the neural differentiation of P19 embryonic carcinoma cells using a microarray-based method called MIAMI. We found a genome-wide demethylation of genes. This suggests demethylation rather than methylation is important in neural differentiation.

元の言語English
ページ(範囲)185-191
ページ数7
ジャーナルJournal of Human Genetics
53
発行部数2
DOI
出版物ステータスPublished - 2008 2 1

ASJC Scopus subject areas

  • Genetics(clinical)
  • Genetics

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