Gene and protein expressions of type I collagen are regulated tissue-specifically in rat hyaline cartilages in vivo

Yasuyuki Sasano, Ichiro Takahashi, Jing Xu Zhu, Haruo Ohtani, Itaru Mizoguchi, Manabu Kagayama

研究成果: Article査読

2 被引用数 (Scopus)

抄録

The present study was designed to investigate how rat hyaline cartilages at various sites in vivo express the gene and protein of type I collagen using in situ hybridization and immuno-histochemistry. The gene of pro alpha 1(I) collagen was expressed by chondrocytes in articular cartilage, and the protein of type I collagen was identified in the cartilage matrix. In contrast, growth plate cartilage expressed the gene of pro alpha 1(I) collagen, but no protein of type I collagen. Neither gene nor protein of type I collagen was expressed in cartilages of trachea and nasal septum. The present study suggested that expression of type I collagen in hyaline cartilages may be regulated tissue-specifically at gene and/or protein levels.

本文言語English
ページ(範囲)149-154
ページ数6
ジャーナルEuropean Journal of Morphology
39
3
DOI
出版ステータスPublished - 2001 12 1

ASJC Scopus subject areas

  • 解剖学
  • 農業および生物科学(その他)

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