Gastric small cell carcinoma with marked response to neoadjuvant chemotherapy

Yasuhiro Nakamura, Setsuya Otani, Michiro Otaka, Tomoyuki Shimada, Satsuki Takahashi, Masahiro Saito, Tohru Takahashi, Masahumi Komatsu, Toshie Suzuki, Shunji Okubo, Masato Hayashi, Hironobu Sasano

研究成果: Article査読

16 被引用数 (Scopus)

抄録

We report a patient with gastric small cell carcinoma (SCC) who showed a marked response to neoadjuvant chemotherapy. The patient was a 72-year-old Japanese man who was admitted because of epigastralgia. Subsequent examination revealed the presence of advanced gastric carcinoma in the lesser curvature of the lower body of the stomach, with multiple abdominal lymph node metastases. Endoscopic biopsy specimens from the tumor revealed SCC with moderately differentiated adenocarcinoma. The patient received neoadjuvant chemotherapy consisting of carboplatin (400 mg/m2, for 1 day), epirubicin (27 mg/m2, for 1 day), etoposide (70 mg/m2, for 3 days), and 5-fluorouracil (330 mg/m2, for 11 days). Clinically, the primary tumor and lymph node metastases were markedly reduced. Subsequently the patient underwent curative surgery and was alive without recurrence for more than 3 years after the surgery.

本文言語English
ページ(範囲)348-352
ページ数5
ジャーナルInternational Journal of Clinical Oncology
10
5
DOI
出版ステータスPublished - 2005 10
外部発表はい

ASJC Scopus subject areas

  • 外科
  • 血液学
  • 腫瘍学

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