Gassericin A; an uncommon cyclic bacteriocin produced by lactobacillus gasseri LA39 linked at N- and C-terminal ends

Yasushi Kawai, Tadao Saito, Haruki Kitazawa, Takatoshi Itoh

研究成果: Article査読

75 被引用数 (Scopus)

抄録

Gassericin A, a bacteriocin that was produced by Lactobacillus gasseri LA39, was treated with lysylendopeptidase and 3-bromo-3-methyl-2-(2-nitrophenyl-mercapto)-3H-indole. The fragments were recovered by SDS-PAGE and sequenced. All amino acids of gassericin A were distributed by sequence analysis and the bacteriocin did not contain any modified amino acids. The amino acid sequence of gassericin A completely coincided with that found through the cloning of the structural gene. Gassericin A was shown to be a cyclic bacteriocin (class II) which is bound at the N- and C-terminal ends. This is the first example of a cyclic bacteriocin from lactobacilli lactic acid bacteria.

本文言語English
ページ(範囲)2438-2440
ページ数3
ジャーナルBioscience, Biotechnology and Biochemistry
62
12
DOI
出版ステータスPublished - 1998

ASJC Scopus subject areas

  • バイオテクノロジー
  • 分析化学
  • 生化学
  • 応用微生物学とバイオテクノロジー
  • 分子生物学
  • 有機化学

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