Functional regulation of biomolecule using DNA-conjugation.

Takahisa Anada; Takeshi Kano; Wataru Kaku; Yoshiki Katayama; Mizuo Maeda; Masaharu Murata

doi:10.1093/nass/2.1.269

Functional regulation of biomolecule using DNA-conjugation.

Takahisa Anada, Takeshi Kano, Wataru Kaku, Yoshiki Katayama, Mizuo Maeda, Masaharu Murata

歯学研究科・歯科学専攻

研究成果: Article › 査読

2 被引用数 (Scopus)

抄録

3'-methacryloyl-oligodeoxynucleotide having antisense sequence against messenger RNA of green fluorescent protein and N-isopropylacrylamide were co-polymerized. The conjugate can reversibly change its conformation at around a transition temperature, similarly to N-isopropylacrylamide homopolymer. We achieved artificially regulation of gene expression depending on temperature using the conjugate.

本文言語	English
ページ（範囲）	269-270
ページ数	2
ジャーナル	Nucleic acids research. Supplement (2001)
号	2
DOI	https://doi.org/10.1093/nass/2.1.269
出版ステータス	Published - 2002

ASJC Scopus subject areas

医学（全般）

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10.1093/nass/2.1.269

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AU - Murata, Masaharu

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Functional regulation of biomolecule using DNA-conjugation.

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