Functional Monomers and Polymers CLXXVII. Synthesis and Interaction Studies of Water Soluble Nucleic Acid Analogs: Polyethyleneimine Derivatives Containing Uracil and 5- Fluorouracil

Takehiko Wada, Yoshiaki Inaki, Kiichi Takemoto

研究成果: Article査読

7 被引用数 (Scopus)

抄録

Nucleic acid analogs were prepared by grafting uracil and 5-fluorouracil de rivatives containing a hydroxy group onto linear polyethyleneimine. The polymers contained about 90 unit% of the nucleic acid bases, and were freely soluble in water at neutral pH value. They were found to form polymer com plexes with polynucleotide by specific base-base interaction in aqueous solu tion.

本文言語English
ページ(範囲)25-41
ページ数17
ジャーナルJournal of Bioactive and Compatible Polymers
4
1
DOI
出版ステータスPublished - 1989 1
外部発表はい

ASJC Scopus subject areas

  • バイオエンジニアリング
  • 生体材料
  • ポリマーおよびプラスチック
  • 材料化学

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