Fulminant hepatic failure in a case of autoimmune hepatitis in hepatitis C during peg-inferferon-alpha 2b plus ribavirin treatment

Takayuki Kogure, Yoshiyuki Ueno, Koji Fukushima, Futoshi Nagasaki, Jun Inoue, Eiji Kakazu, Yasunori Matsuda, Osamu Kido, Yu Nakagome, Osamu Kimura, Noriyuki Obara, Yuta Wakui, Takao Iwasaki, Tooru Shimosegawa

研究成果: Article査読

28 被引用数 (Scopus)

抄録

A 27-year-old Caucasian female with hepatitis C virus (HCV) infection treated with interferon (IFN) who developed severe autoimmune hepatitis (AIH) is described. The infecting viral strain was of genotype Ib and the pre-treatment HCV viral load was at a high level. The patient was treated with pegylated IFN-alpha 2b and ribavirin, and her HCV-RNA became negative at wk 12, but after that she developed fulminant hepatic failure. The patient recovered after steroid pulse therapy consisting of methylprednisolone 1000 mg/d for three days which was administered twice. A needle liver biopsy revealed the typical pathological findings of AIH.

本文言語English
ページ(範囲)4394-4397
ページ数4
ジャーナルWorld Journal of Gastroenterology
13
32
DOI
出版ステータスPublished - 2007 8月 28

ASJC Scopus subject areas

  • 消化器病学

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