Fluorescence polarization-based multiple samples detection using microchamber array towards high-throughput molecular interaction analysis

O. Wakao, M. Maeki, A. Ishida, H. Tani, Akihide Hibara, M. Tokeshi

研究成果: Conference contribution

1 被引用数 (Scopus)

抄録

We report a new high-throughput homogeneous assay format using a microchamber array towards molecular interactions analysis. The assay format is based on the fluorescence polarization (FP) detection using liquid-crystal display (LCD) that can switches a direction of FP by changing its images. In this work, we demonstrate a multiple sample FP immunoassay (FPIA) of prostaglandin E2 in a microchamber array to simultaneously analyze 25 samples. FP signals were imaged simultaneously and their values were acquired separately. This result showed our format with high-throughput had a measurement performance comparable to that of a conventional apparatus designed to single analysis.

本文言語English
ホスト出版物のタイトル20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
出版社Chemical and Biological Microsystems Society
ページ1400-1401
ページ数2
ISBN(電子版)9780979806490
出版ステータスPublished - 2016
イベント20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland
継続期間: 2016 10 92016 10 13

Other

Other20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
国/地域Ireland
CityDublin
Period16/10/916/10/13

ASJC Scopus subject areas

  • 制御およびシステム工学

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