Flow of red blood cells through a microfluidic extensional device: An image analysis assessment

T. Yaginuma, A. I. Pereira, P. J. Rodrigues, R. Lima, M. S.N. Oliveira, T. Ishikawa, T. Yamaguchi

研究成果: Conference contribution

2 被引用数 (Scopus)

抄録

The present study aims to assess the deformability of Red Blood Cells (RBCs) under extensionally dominated microfluidic flows using an image based technique. For this purpose, a microchannel having a hyperbolic shaped-contraction was used and the images were captured by a standard high-speed microscopy system. The images acquired display RBCs with various light intensity levels and image analysis was used to quantify the Deformation Index (DI) of the RBCs considering these light intensity differences. Additionally, the velocities of different intensity-level RBCs flowing along the centerline of the channel were measured using particle tracking velocimetry. The preliminary results at two different flow rates reveal a highly deformable nature of RBCs when submitted to strong extensional flows. It was also observed that the low intensity cells exhibit a slightly higher velocity than intermediate intensity cells, which we attribute to the cells being located in different planes.

本文言語English
ホスト出版物のタイトルComputational Vision and Medical Image Processing, Proceedings of VipIMAGE 2011 - 3rd ECCOMAS Thematic Conference on Computational Vision and Medical Image Processing
ページ217-220
ページ数4
出版ステータスPublished - 2012 2 13
イベント3rd ECCOMAS Thematic Conference on Computational Vision and Medical Image Processing, VipIMAGE 2011 - Olhao, Algarve, Portugal
継続期間: 2011 10 122011 10 14

出版物シリーズ

名前Computational Vision and Medical Image Processing, Proceedings of VipIMAGE 2011 - 3rd ECCOMAS Thematic Conference on Computational Vision and Medical Image Processing

Other

Other3rd ECCOMAS Thematic Conference on Computational Vision and Medical Image Processing, VipIMAGE 2011
国/地域Portugal
CityOlhao, Algarve
Period11/10/1211/10/14

ASJC Scopus subject areas

  • コンピュータ ビジョンおよびパターン認識
  • 生体医工学

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