Fiber-based polarization-sensitive OCT for birefringence imaging of the anterior eye segment

Masahiro Yamanari, Satoru Tsuda, Taiki Kokubun, Yukihiro Shiga, Kazuko Omodaka, Yu Yokoyama, Noriko Himori, Morin Ryu, Shiho Kunimatsu-Sanuki, Hidetoshi Takahashi, Kazuichi Maruyama, Hiroshi Kunikata, Toru Nakazawa

研究成果: Article査読

27 被引用数 (Scopus)

抄録

We demonstrate a prototype system of polarization-sensitive optical coherence tomography (PS-OCT) designed for clinical studies of the anterior eye segment imaging. The system can measure Jones matrices of the sample with depth-multiplexing of two orthogonal incident polarizations and polarization-sensitive detection. An optical clock is generated using a quadrature modulator and a logical circuit to double the clock frequency. Systematic artifacts in measured Jones matrices are theoretically analyzed and numerically compensated using signals at the surface of the sample. Local retardation images of filtering blebs after trabeculectomy show improved visualization of subconjunctival tissue, sclera, and scar tissue of the bleb wall in the anterior eye segment.

本文言語English
ページ(範囲)369-389
ページ数21
ジャーナルBiomedical Optics Express
6
2
DOI
出版ステータスPublished - 2015

ASJC Scopus subject areas

  • Biotechnology
  • Atomic and Molecular Physics, and Optics

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